Living and working in Tampa, Florida, as we do, we witness on a weekly basis at least one patient who displays signs of mold sickness and depression. We can put much of the blame for this malady on water-damaged buildings, which are found in abundance in our humid, damp, tropical southern climate. Because of these climate-specific surroundings, we almost always ask our patients about their living and working environment because we are strong believers in the notion that there is a direct link between water-damaged buildings that can cause mold sickness and associated depression. Mold-related Signs of Depression Some signs of depression — no matter the cause — often include the following: